Sildenafil citrate and Duloxetine are the two active ingredients that trigger the reaction that results in a hard on. The two active ingredients help relax the muscles and dilate the veins of the penis to assist in stronger erections, and this happens in conjunction with a sexual simulation.
To some extent, the drug combination is very effective in treating male impotence. However, it should be remembered that the drug can only work if an external simulation is given. Sildenafil citrate and Duloxetine are two antidepressant medications that also keep a person sexually active.